![]() ![]() Wildcard characters can be used to help with word games like crosswords and scrabble where only some of the letters are known, or you have to find an anagram, or with spelling. Then you can follow the links in the definition page to get more word definitions. As you type, Dictionary homes in on the word you are looking for. The home page contains a randomly selected word cloud which will pique your curiosity and help you improve your vocabulary, while the search box allows you to find specific words easily. The dictionary definitions are stored locally, and because it's ad-free there's no need for a network connection. Dictionary is ideal for both native English speakers and English learners or people studying the English language. You will love playing with other players worldwide.ĭictionary is a free offline English dictionary containing over 200,000 words and definitions and no ads. Hearts online games with friends is an addictively fun and enticing trickster card wars. Hearts Online: Multiplayer Solitaire free Card Games features flexible user setting options, table and deck designs to choose from, and intuitive statistics and scoreboard options to ensure that competitive gamers and casual players alike see exactly how they’re playing cards in every game in this package with ease. ![]() decks, discovering new ways to have fun, and play Hearts your way with different trickster cards games - the best of all Hearts Card Games or Solitaire card wars online multiplayer games. □ Enjoy this Hearts Online Multiplayer Games with friends and live players worldwide!ĭownload Hearts Online Card Games and Start organizing avatars, and tables. ❤ Spin the Wheel - You can win Millions of Coins! ❤ Play the spades card game free with different tables □ Get your best Game Avatar from a wide range of selections ✌️ Login with Facebook and share your success and play spades with friends. □ Leaderboards - Keep Winning to Become the King of Hearts card classic! □ Tournaments - Become the King of Hearts card classic! □ 7 Different online games with friends Leagues: Golden, Platinum, Diamond, Millionaire, Billionaire, Master, and Grand Master. ⚡ Standard Game to 100 Points and Quick Game just 1 Round Hearts Online: Multiplayer Solitaire free Card Games is packed with amazing features to help you have a seamless game experience. You can win free coins on the hearts online games with friends. Keep playing cards and get on top of the leaderboard. Hearts Online: trickster cards Games allows you to play Hearts game with different game leagues:Įach of these leagues allows you to place different bets. You will never get bored while playing this spades online hearts multiplayer card games. The Winner is whoever has fewer points than the other Players. In the Quick Mode, you will play only 1 Round. In Standard Mode, the hearts card game free with many rounds until one of the Players makes 100 Points. You can start playing Hearts card wars online games with friends in either of the below game modes: You can play the spades card game free with coins and the game also has different ways to earn coins. Enjoy this hearts card game free with live players worldwide. If you like playing solitaire games or cribbage classic hearts games, you will love playing the Hearts card wars online games with friends. You can play and compete with other players' spades online on this Hearts card classic game. Hearts Online: online multiplayer games and Solitaire free Card Games is one of the best online multiplayer online card games with 7 different game leagues and leaderboards features. Cards must be placed in the foundations from Ace all the way through King.Do you love card games? Do you want to play the best trickster cards games - Solitaire games or cribbage classic Hearts Card Games? Start playing this amazing hearts card game free where you can play online multiplayer trickster cards, and game leagues, with other players online Hearts card classic. The stock card pile will deal solitaire players only one card at a time though players are allowed unlimited passes through the deck! You will have won Patience Solitaire when all of the cards have been added to the four foundations. Players of Patience Solitaire can click on their reserve cards at the top left hand of the solitaire board for more card options. Play Patience Solitaire by making stacks of cards, stacks will cascade towards the bottom of the solitaire board and are to be comprised of red, black, red, black, red, black cards. Play One Card Patience Solitaire as often as you like and always be improving your Patience Solitaire skills! Keep track of your ever increasing solitaire accomplishments online as Card Game will automatically record your high score! Welcome to Card Game, a smorgasbord of all things Patience Solitaire! Stimulating and best of all free(!) 24/7 Games Patience Solitaire games are always available for your playing pleasure. ![]()
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![]() In the context of these ceremonies, the San Pedro experience is known for being empathogenic (similar to MDMA) and potentially life-changing, promoting radical introspection, healing, and a sense of wonder and awe. San Pedro has been an important element to the spiritual ceremonies of various indigenous cultures for thousands of years. In the right circumstances, they offer up the key to unshackle the mind, and allow it to grow - taking them way beyond their traditional recreational use.San Pedro ( Trichocereus/ Echinopsis pachanoi) is a thin, columnar cactus native to the Andes mountains in South America (Argentina, Bolivia, Colombia, Chile, Ecuador and Peru) that contains mescaline-one of the longest-studied psychedelics in the world-and the first to be labeled with the term “psychedelic.” Psychedelics As A Tool For Self Growth And Spirituality Beloved by psychonauts and ordinary horticulture enthusiasts, we take a closer look at this trippy cactus. The crested San Pedro cactus is the visually stunning mescaline cactus of Peru. The alkaloid can be found in a variety of cactus species. Mescaline occupies the esteemed podium of naturally occurring hallucinogens along with DMT and psilocybin. Follow these guidelines whether you just want to giggle uncontrollably for a while or give your. Here at Zamnesia, we want to make sure you have a good trip on your first plummet down the rabbit hole. How To Prepare For A Safe Psychedelic Trip? The cacti have entheogenic value as they contain the psychedelic compound mesc. San Pedro cactus grows tall and mighty and can serve as an impressive and towering ornament in any garden or green house. How To Grow And Care For San Pedro Cactus This is traditionally seen as a form of “cleansing” that ensures your body and spirit are “clean” for the trip ahead. However, San Pedro can still make users feel nauseous and even cause vomiting before the trip kicks in. San Pedro tastes only slightly bitter, and the obligatory nausea that goes hand-in-hand with peyote is not as likely to occur. The effects of San Pedro are, compared to peyote, said to be much more pleasant the peak is less mind-boggling and not nearly as physical. Effects kick in about 1–2 hours after ingestion and peak for another 2–4 hours before tapering down for another 8 or so hours. Overall, the experience is likened to that of other hallucinogens due to the sense of spiritual insight and connectivity that pervades. This last one is of particular interest to many mescaline users as the substance can elicit visual patterns of various types. As such, the cactus is used in both a recreational and spiritual context up to this very day.Īlthough the effects of psychedelic substances can be hard to accurately quantify, common effects experienced on San Pedro include: return of long-forgotten memories, extreme sensitivity to light and colour, synesthesia, altered perception of time, and open and closed-eye visuals. While today the San Pedro is enjoyed around the world as a natural psychedelic, indigenous Andean cultures long used the cactus in for divination purposes. Mescaline is a hallucinogen with effects that range from euphoria to full-blown, vivid hallucinations. ![]() ![]() ![]() I think it was Soundforce Mac that was *slightly* better, because it had a "copy & paste selection to new file," but then you still had to save that file as an additional command, and that still slows things down notably and results in various window-jumping compared to audition's 1-command approach (crucial when doing LOTS of sampling at once). Apple may provide or recommend responses as a possible solution based on the information provided every potential issue may involve several factors not detailed in the conversations captured in an electronic forum and Apple can therefore provide no guarantee as to the. The software client turns Spotify into a native Progressive Web Application for computers. Xpotify is a music and radio software by Mahdi Ghiasi. Wix Best Adobe Dreamweaver alternative overall Specifications Free version: Yes Difficulty: Easy Todays Best Deals Wix Pro 23. This site contains user submitted content, comments and opinions and is for informational purposes only. Seamless Integration of Spotify to Computers. ![]() I used to use WaveBurner to do it, but I just can't hear the difference. Best alternatives to Adobe Dreamweaver 2023 (Image credit: Wix) 1. I've even been dithering down the stereo L/R to 16/44.1 in PTLE. I'm doing all my editing and mixing inside PTLE. Most other audio editors seem to rely on archaic processes where you have to copy+paste and save, executing tons of commands rather than just One. I've been using WaveBurner to assemble the entire 'CD' and then just apply a little eq or comp/limit to make all the tracks 'fit'. in Audition I select, right click, "Save Selection as New Audio file.") For sampling movies and other audio sources, that's a must have. A relatively affordable alternative is Audio File's new Triumph Software. Basic workflow processes became longer to perform (my most important one = select a range of audio in a file and be able to save it as a separate file immediatley e.g. a good application for creating Red Book standard CDs called Waveburner. the changes after the big name change totally threw me and I never recovered. Waveburner was designed to be easy to use, just like iMovie and so on, and that means removing technical decisions that the average Joe could make a mess of. Waveburner was an excellent piece of software, I agree. I still never figured out how to get along with Triumph. I believe it was dropped during the transition from Logic 8 to 9. Tarekith wrote:Triumph is $80, and you get some of the best SRC and dithering included with the iZotope settings. ![]() ![]() ![]() It is low in calories, a good source of dietary fiber, and is fat-free.The cookies is used to store the user consent for the cookies in the category "Necessary". Okra is a good source of vitamin C and A, also B complex vitamins, iron and calcium. You can't get rid of this quality by soaking or overcooking. If you object to this quality, don't eat okra. Remember, okra is slimy and sticky - it is supposed to be that way. The flavor blends well with acid foods such as tomatoes. When the pods are cut, they exude a mucilaginous (thick and sticky) juice that is an excellent thickener for stews and soups, especially Créole Gumbo. Avoid long cooking times unless you are making soups, stews or gumbo. Because of its similar flavor, it can be used in place of eggplant in many recipes. Okra can also be steamed, baked, pickled, boiled or stewed. Sauté with corn kernels, onion and sweet peppers. Very young, tender pods can be sliced, dipped in egg, breaded with corn meal and fried (a favorite here in the Southern U.S.). Mature okra is used to make rope and paper! (Avoid those old woody pods!). When preparing, remember that the more it is cut, the slimier it will become. It does not store well, so use within 2 or 3 days at most.ĭo not wash until ready to use, or it will become slimy. Store in a paper bag in the warmest part of refrigerator, as temperatures below 45 degrees can damage okra. Avoid pods that are dull and dry looking, blemished or limp. The best varieties are a rich green color. Okra comes in varying shades of green (there is also a new red variety), and can be smooth or have a ribbed surface. They must be picked about 4 to 5 days after flowering, when 4 inches or so in length, before they mature and toughen. The pods grow rapidly, being ready for harvest in about 60 days of summer weather, when grown from seed. It is available year-round, with a peak season during the summer months. Okra is a tropical plant which grows best in warm climates. It grows well in the southern United States where there is little frost.ĭue to increased interest in American regional foods, these bright green, tender pods have gained more respect as a vegetable in the U.S., aside from its use as a thickener. Okra is commonly associated in Southern, Creole, and Cajun cooking since it was initially introduced into the United States in its southern region. It is not a very common vegetable in most European countries, except for Greece and parts of Turkey. Today okra is popular in Africa, the Middle East, Greece, Turkey, India, the Caribbean, South America and the Southern U.S. ![]() In Louisiana, the Créoles learned from slaves the use of okra (gumbo) to thicken soups and it is now an essential in Créole Gumbo. in the 1700s, probably brought by slaves from West Africa, and was introduced to Western Europe soon after. The seed pods were eaten cooked, and the seeds were toasted and ground, used as a coffee substitute (and still is). Its cultivation spread throughout North Africa and the Middle East. Okra probably originated somewhere around Ethiopia, and was cultivated by the ancient Egyptians by the 12th century B.C. The pods, when cut, exude a mucilaginous juice that is used to thicken stews (see Gumbo), and have a flavor somewhat like a cross between asparagus and eggplant. These tender, unripe seed pods are used as a vegetable, and have a unique texture and sweet flavor. ![]() The seed pods are 3 - 10 inches long, tapering, usually with ribs down its length. It has heart shaped leaves (one species is cultivated for its edible leaves), and large, yellow, hibiscus-like flowers. It is a tall (6 ft) annual tropical herb cultivated for its edible green seed pod (there is also a red pod variety, which turns green when cooked). Okra is a member of the Mallow family, related to cotton, hibiscus and hollyhock. See Also: Okra, Vegetable of the Month Okra Trivia Okra Recipes The term okra was in use in English by the late 18th century. The name 'okra' probably derives from one of the Niger-Congo group of languages (the name for okra in the Twi language is ‘nkuruma’). In Spanish okra is ‘quibombo’ the French word is ‘gombo,’ ‘bamia’ or ‘bamya,’ in India it is ‘bhindi,’ and in the eastern Mediterranean and Arab countries ‘bamies’. Also known as: Lady's Fingers, gombo, gumbo, quingombo, okro, ochro, bamia, bamie, quiabo. ![]() ![]() ![]() ![]() It’s the closest direct alternative to EndNote, and also offers a “cite as you write” plug-in for Word (and Word for Mac). Once you’re ready to build a bibliography, just access your Mendeley library, import any outside sources, and select a referencing style – Mendeley does the rest and builds a perfect citation page for your paper. Mendeley is an “all-inclusive” reference manager, allowing you to first find relevant documents and publications, annotate them as you read, and then easily add them to your library for later reference. It’s free to start and use with up to 2GB of storage, with fairly-priced tiers at 5GB, or go beyond with unlimited storage. Mendeley comes close to the power of EndNote at potentially a fraction of the cost – their pricing model removes the flat license fee and instead bills you monthly based on how much storage you require. On that note, we reach the main crux of EndNote – it’s far from affordable with no introductory pricing or easily-accessible free trial, and though there is a student discount, its hefty price tag is likely to put it out of reach for most undergraduate or graduate students. It’s not particularly user-friendly, and a vast majority of EndNote users never come close to actually making the most of the platform or taking advantage of what they paid for. Considering that their audience is trying to simplify their workflow, taking a seminar just to learn how to begin using the tool is not a particularly attractive offer. EndNote has had to create a fully fleshed out “Training Channel” on YouTube just to teach users how to begin using the software. With all that reference managing power comes an unfortunate dose of complexity. Installation: Desktop application, Microsoft Word plug-in Why Not EndNote? It also pairs nicely with Microsoft Word through its “Cite While You Write” plugin, automatically generating a bibliography while you make in-text citations.Ĭost: $299 physical, $249 digital license So if those are your biggest hurdles, EndNote might be perfect for you!ĮndNote integrates many platforms to offer powerful search functionality across a detailed online archive of sources and PDFs. EndNote tackles what it believes are the biggest challenges for its user base, namely (1) the tedious work of manually collecting citations and formatting bibliographies, and (2) remotely coordinating this curation of citations with your colleagues. The challenge? Finding the perfect one for you and your workflow.ĮndNote (or more specifically, “EndNote X9”) has become the go-to in reference management for researchers and scientists, and is beginning to drip down to the student level. The academic lifestyle is a stressful one! Whether you’re in need of a note-taking tool, a reference manager, or an all-around knowledge organizer, you have an incredible array of digital tools at your disposal. Regardless of your level of mastery – from undergraduate, to doctoral candidate, to veteran researcher, professor, or academic author – writing the perfect paper is a near impossible goal. ![]() Not in the mood for a long read? Skip to the summary – TL DR. But is it truly the most effective, or just the most popular? And for academics on a budget (which, let’s be honest – we all are), does the high ticket price force you to look elsewhere? This article first explains what academic software solutions are used for, then breaks down the pros and cons of EndNote, Zotero, Mendeley, ReadCube, and of course, Auratikum! This will import your Mendeley records and any PDF attachments from your Mendeley collection into this new EndNote library.EndNote has become an important tool in the belts of researchers, scientists, and students around the world. Change the Import option to Reference Manager (RIS). ![]()
![]() It is considered the world’s oldest typeface as its design comes from the lettering carved into Trajan’s Column in Rome. Though Trajan’s Column rarely gets much use in modern graphic design, it signifies an important style in history. Influential Typefaces and Their Design History These assumptions are based on common themes we see every day. You may inherently know that a law firm would probably use a serif typeface, a fancy clothes store may use script, and that a fast-food brand would probably use a sans serif. Even if you are not a designer, sometimes a design choice can make you draw conclusions about a company, person, or piece of media. It requires a balance between versatility and expressivity… everyday accessories, and special outfits for special occasions.” Typography helps us convey ideas that we cannot directly express. ![]() French type designer Jean-Baptiste Levee explains that “building a good font collection is like populating one’s wardrobe. There is a need for a wide array of fonts, but you might be wondering why. Some say that script is a fourth category while others claim it fits under decorative. The last category includes decorative typefaces that have other details purely for ornamentation. Sans serif simply refers to text that does not include serifs. Though many minimalists would never use a serif design (thinking it adds unneeded decoration), serif typefaces tend to be more legible than sans serif and are often used in books or printed works. A serif is an extra bit of detail at the end of a letter reminiscent of a foot or hat. The first two categories are the most well-known: serif and sans serif. ![]() It is also important to know that there are three major kinds of typefaces. ![]() ![]() Just like you can drag any file to tidy up your desktop or add it to an email.Īs you can see, taking a screenshot on a Mac of both images and videos is very simple. You can drag this thumbnail into a folder to save it, or even drag it into a conversation to share it quickly. What if I want to save your screenshot somewhere else? When you take a screenshot on a Mac, the screenshot will appear as a thumbnail at the bottom of the screen. Now that you know how to screen record on your Mac, you may be wondering where to save this file on a Mac. Where does this screen recording save on a Mac? Other options on how to record the screen on your Mac, that will appear in this bar, are the options to activate the timer, perfect for when you want to capture something in detail without having to edit the video later or the option to choose where to save that screen recording on your Mac, so you will always know where you saved it!Īnd to stop recording? Simply click on the stop button in the menu bar. This Mac screen recording is very useful if you want to record part of a YouTube video to save it on your Mac or if you want to explain to someone the steps or tricks they can use on their Mac to do a particular thing.īy pressing these three keys, a menu bar will appear where you can choose whether to record the whole screen or just a part of it. Remember to press all three keys at the same time! If you are looking for how to record the screen on Mac, all you have to do to record a video of your Mac screen is press Shift + Command + 5. It is as intuitive as using the copy and paste functions in a document. If you press Shift + Control + Command + 4 at the same time, you will take the screenshot on your Mac and you can send it or add it to a document by simply pasting it. Here’s one way you can keep your desktop from getting cluttered! If you take a lot of screenshots, either to add comments to your notes or send them to friends, you might have a desktop full of screenshots on Mac. What if you have selected the wrong area? Don’t worry! You can easily cancel the screenshot on a Mac by pressing the Esc key (Escape). To take a screenshot on a Mac, just release the mouse or trackpad button, and you’re done! Screenshot taken!. ![]() ![]() Drag this cross to select the area of the screen you want to capture.When you press these keys, a cross will appear on your Mac screen to allow you to select a part of the screen. ![]()
![]() ![]() We invest more in R&D than anyone else in the industry, so there's always a new release around the corner. There’s a reason that the award-winning research scientists, design gurus, and visualization experts choose Tableau. The new functionality is bound to dynamic. Tableau's software moves as fast as you do. One of the most anticipated functionality by Tableau Desktop users domes with the new Tableau 2020.1 version. This definitely maximizes the potential of any data warehouse. In Tableau Desktop version 2020.1, Tableau addressed what has been the number one feature request for at least 6 years (as long as Ive been using Tableau). ![]() You can directly connect to your data and perform real-time queries and analysis, without having to write any code. At the sign-in prompt, I enter the ID and site (no password, as we are SAML-authenticated). This new functionality opens some doors that will allow us to perform multiple pivots. Blank login screen in Desktop when connecting to Tableau Online Good morning I am having trouble publishing a data source from Desktop 2020.14 to Tableau Online. In particular, the whole process does not require any wizards or scripts. For example ComputerHKEYLOCALMACHINESOFTWARETableauTableau 2020.1 Right-click on your Tableau version and select New > Key and name it DiscoverPane. However, things have changed now that Tableau has introduced the new data model/relationships in 2020.2 (Note: If you’re not yet familiar with the new data model, I’d suggest reading my blog on the topic, Tableau's New Data Model, before you proceed). This includes Tableau Desktop 2020.1 or later and Tableau Prep 2020.4.1. This enables users to identify some trends of data in a visual way in seconds. Before you start you must have installed a supported Tableau application. 32-piece shading profundity required What’s new in Tableau Desktop 2020.1. ![]() In addition to professional technology, more importantly, it’s a foolproof tool that can make externalization and visualization process to complex data, so that ordinary users are able to easily show their complex data in hand in a professional way with all sorts of graphs.Īs a very fast, user-friendly and self-service data analyzing & processing tool that everybody can use, Tableau Desktop is based on breakthrough technologies, which can convert database queries to data charts to cater to human talent for observing graphic patterns. Observe: Tableau Desktop Pro 2020 Full Crack most recent Software Free Download System Requirements: Mac+ Windows XP, Vista, 7, 8, 8.1, and 10. Tableau Desktop is a famous and very powerful data analysis & visualization leader. This change also applies to companion client software for these versions, including Tableau Desktop, Tableau Prep, Resource Monitoring Tool, Content Migration Tool, and others. Free download Tableau Desktop 2020.1.2 Professional Edition full version standalone offline installer for Windows PC, Tableau Desktop Overview We recommend using the newest maintenance release of this version, which contains additional fixes. ![]() ![]() ![]() What is Diptrace?ĭiptrace is an ECA/CAD software to build schematic design and the printed circuit board. You can quickly create any schematics and then change it to the other formats, i.n e., PCB.ĭiptrace allows the user to use primary and flexible features like 3D modeling, high-speed shape-based routing, and extensive import/export capabilities. While switching from one format to another format, it also assembles the electrical components. It offers multi-sheet and multi-level hierarchal circuits Diptrace has four modules. Its functionality details are described in the following sections. You can also check out a detailed guide about Diptrace software. zlib is free and super easy to use.The schematic capture section allows the user to connect the pins visually, without wires, logically or using the net ports embedded in the circuit board. 11325 files, 8.68 GB Maybe try InnoSetup instead of qSetup. the files are unpacked by installer in c:\Users\\AppData\Local\Temp\\ at least on Windows 7. However, because the installer insists on unpacking itself first, it crashed without any significant error message if there's not enough free disk space. ![]() so those 8-10 GB would normally fit in those 5 GB of free disk space. I could start the setup, select install folder and enable NTFS compression on that folder, and as the installer copies files, they're real time compressed. ![]() Let's say I had DipTrace installed on my SSD drive with only 5 GB of free space. Don't see why the 1.5 GB has to be unpacked to 8-10 GB in a temporary folder, only to have it copy files to destination folder later. installer crashed without error messages (gets stuck and clicking next doesn't do anything) I had only 5 GB free space on the boot drive, and the installer defaults to boot drive to unpack itself. I have a 120 GB SSD as boot drive that was kinda full. really need to work a bit on your installer for the models. zip or 7zip archives can be easily parsed to retrieve the file listing ( and extracting files from 7zip is as fast as zip as long as solid mode compression is unchecked), and the 3d viewer could easily extract (and cache in ram if needed) only the models used by the active project. just by enabling NTFS compression on the folder the size shrinks to half, so the content is very compressible. Is there any particular reason why the 3d models can't be "installed" as zip/7zip/whatever packs, maybe grouped by manufacturer or category instead of having hundreds of files that are basically very verbose, text files? Reason is altogether the use a bit of disk space, they unpack in around 8-10 GB. I went with KiCad because of limitations in Eagle and DT, that KiCAD had at the time, yes they have since been implemented but that was my reason at the time to drop them, and when you spend a decent amount of time learning a new tool you kind of stick to it, I have EAGLE 7 installed for legacy, removed DT a long time ago, nobody in the hobbyist community I have seen uses it for OSHW projects, so I had no need for it. ![]() Say what you want about DT/EAGLE/KICAD the truth is they can all perform mostly the same functions as each other, it's just what you find easier to use and what you are willing to pay or not pay for. And just hope that it gets added in the future. Yes it is frustrating when simple things are missing like as the mentioned dashed/dotted line feature, but you have 2 choices, live with that limitation or use a different tool. I would always recommend trying EAGLE, DipTrace and KiCAD to anyone though as despite what YOU think, others might get on better with a n other package. PCB tools mostly are preferential, be it picked up as a hobbyist or introduced it via work, I wouldn't go back to DT just because I am used to other tools (Altium and KiCAD), if I were to go back to Eagle it'd have to be V7 before Autodesk messed it up, as the "new features" are really not worth (for me) the pure amount of crap they have injected into it since. You pay your money, you take your choice. ![]() ![]() ![]() One gene ( lin-14) was a protein-coding gene, as expected the biological activity of the other gene (lin-4, which represses lin-14) was unexpectedly caused by a short RNA molecule rather than a protein. As an early example, while studying genes responsible for developmental timing in Caenorhabditis elegans, the Ambros and Ruvkun groups identified two genes, lin-4 and lin-14, as necessary for appropriate development ( 90, 184). This understanding is built in part on discoveries in which genes for ncRNAs (rather than protein-coding genes) were identified as master regulators of certain biological phenomena. The much broader scope of ncRNA-directed activities, including regulation of chromatin, is now widely appreciated. The roles of the first ncRNAs discovered involved RNA translation and RNA processing (reviewed in 25). Non-protein-coding RNA transcripts (ncRNAs) have been known to regulate gene expression since the advent of molecular biology. LESSONS FROM EARLY DISCOVERIES OF NONCODING RNAs We emphasize areas where challenges remain and where consensus among laboratories has underscored the exciting ways in which human lncRNAs may affect chromatin biology. ![]() In this review, we examine the definition, discovery, functions, and mechanisms of lncRNAs. Although little is known about the biochemical mechanisms of these lncRNAs, there is a developing consensus regarding the challenges of defining lncRNA function and mechanism. There has been dramatic growth in studies focused on the nuclear roles of long noncoding RNAs (lncRNAs). Indeed, this idea is supported by well-established examples of noncoding RNAs that affect chromatin structure and function. RNA is transcribed in the nucleus, so it is logical that RNA could play diverse and broad roles that would impact human physiology. Less clear are the upstream roles of RNA in regulating transcription and chromatin-based processes in the nucleus. HyperTRANSCRIBE is available for Windows or OS X for US$99, when they get it added to their store.Beyond coding for proteins, RNA molecules have well-established functions in the posttranscriptional regulation of gene expression. Once installed, the free version has all of its features fully enabled except the Save, Export, Copy, and Paste commands are disabled and drag and drop from HyperTRANSCRIBE to other programs is disabled. You may download HyperTRANSCRIBE for free. You can export as plain text to use in any program, or Rich Text Format to preserve style information like bold, italics, font size, etc. When you’re done transcribing you can export your transcription for use in other programs. Between sessions the program remembers which file was being transcribed and where the current selection is, so you can pick up where you were when continuing on. HyperTRANSCRIBE keeps track of the current number of characters, words and paragraphs in the transcription. Playback can be looped for review-as-you-go. Users can assign start and end times for a portion of the file in a single keystroke, and advance in segments the user is comfortable with. ![]() When the file is open, control of playback is available using keystrokes so hands never leave the keyboard. HyperTRANSCRIBE opens anything QuickTime opens on Windows or Macintosh such as MP3, AIFF, WAV, MPEG, AVI, MOV, and many other media file types. HyperTRANSCRIBE is a piece of new software designed to ease the process of transcribing video and audio files. ![]() |